Study Summary: Shatavari (Asparagus racemosus) for Perimenopausal Wellness
Main Clinical Study
Study Details
Title: Efficacy and Safety of Shatavari (Asparagus racemosus) Root Extract for Perimenopause: Randomized, Double-Blind, Placebo-Controlled Study
Published In: International Journal of Women’s Health (2025)
Study Type:
• Randomized clinical trial
• Double-blind
• Placebo-controlled
Official Sources
• PubMed Study
• Full PMC Research Article
Background of the Study
Researchers explained that women undergoing:
• Perimenopause
• Hormonal fluctuations
• Stress-related hormonal changes
often experience:
• Hot flashes
• Mood swings
• Fatigue
• Sleep disturbances
• Anxiety
• Reduced quality of life
Because many women seek natural alternatives to hormone therapy, researchers investigated whether Shatavari root extract could safely support hormonal wellness.
Study Design
Participants
• 120 women screened
• 80 eligible women enrolled
• Age group: Perimenopausal women
Participants were divided into:
• Shatavari group (SHT): 40 women
• Placebo group (PL): 40 women
A total of 73 participants completed the study:
• SHT: 37
• Placebo: 36
Dosage Used
Participants received:
• 300 mg standardized Shatavari root extract
• Once daily
• For 8 weeks
Parameters Evaluated
Menopause Rating Scale (MRS)
Evaluated:
• Hot flashes
• Sleep issues
• Irritability
• Anxiety
• Physical discomfort
MENQOL
Menopause-specific quality of life questionnaire.
POMS (Profile of Mood States)
Measured:
• Stress
• Mood
• Emotional wellbeing
PSS (Perceived Stress Scale)
Measured:
• Stress levels
• Emotional burden
Hormone Testing
Blood tests assessed:
• Estradiol
• Follicle Stimulating Hormone (FSH)
• Thyroid hormone (T3)
Safety Testing
Researchers monitored:
• Liver function
• Kidney function
• Adverse effects
Major Findings
1. Significant Improvement in Hormonal Symptoms
Women taking Shatavari showed significant improvement in:
• Somato-vegetative symptoms
• Psychological symptoms
• Urogenital symptoms
This included improvements in:
• Mood fluctuations
• Emotional stress
• Sleep-related complaints
• Hormonal discomfort
2. Reduction in Hot Flashes
Researchers reported:
• Significantly greater reduction in hot flashes in the Shatavari group
• Statistical significance: p = 0.002
3. Stress Reduction and Mood Support
The study found Shatavari supplementation improved:
• Stress scores
• Fatigue
• Vigor
• Emotional wellbeing
Important Statistical Findings
• Stress reduction at week 8: p < 0.0001
• Fatigue improvement: p = 0.019
• Vigor improvement: p = 0.021
4. Positive Effects on Hormonal Markers
Researchers observed increases in:
• Estradiol
• Follicle Stimulating Hormone (FSH)
• T3 thyroid hormone
Statistical Findings
• Estradiol improvement: p = 0.003
• FSH changes: p = 0.028
• T3 improvement: p = 0.021
These hormones are important for:
• Reproductive wellness
• Metabolism
• Mood stability
• Female endocrine health
5. Safety Results
The study found:
• No major adverse effects
• No liver toxicity
• No kidney toxicity
• Shatavari was generally well tolerated
Researchers’ Conclusion
The authors concluded:
“Shatavari root extract may be an effective and safe natural intervention for the treatment of perimenopausal symptoms.”
Additional Published Study on Sexual Wellness
Study Details
Title: Effects of Shatavari Root Extract on Sexual Wellness in Women
Published: 2026 — International Journal of Women’s Health
Official Source
Study Design
• 135 women
• Randomized
• Double-blind
• Placebo-controlled
• 8-week intervention
Key Findings
Women taking Shatavari showed improvements in:
• Sexual satisfaction
• Lubrication
• Arousal
• Orgasm scores
• Mood
• Sleep quality
• Reproductive wellness
Researchers suggested Shatavari may help support:
• Hormone balance
• Female reproductive health
• Emotional wellness during hormonal transitions
How Shatavari Works (Mechanisms Explained)
Researchers describe Shatavari as containing:
• Steroidal saponins
• Phytoestrogenic compounds
• Antioxidant molecules
Potential Mechanisms
Phytoestrogenic Activity
May help support:
• Estrogen-related pathways
• Hormonal balance
• Menopausal comfort
Adaptogenic Effects
May help regulate:
• Stress response
• Cortisol balance
• Emotional wellbeing
Antioxidant Protection
May reduce oxidative stress linked to:
• Aging
• Hormonal imbalance
• Reproductive tissue damage
Scientifically Reported Benefits Across Studies
Published studies suggest Shatavari may support:
• Hormonal balance
• Menopausal wellness
• Stress reduction
• Emotional wellbeing
• Sleep quality
• Hot flash management
• Reproductive wellness
• Female sexual wellness
• Energy and vitality
Important Scientific Note
Researchers also note:
• Studies are still relatively small
• Longer-term research is needed
• Shatavari should not be considered a replacement for prescribed medical treatment in serious hormonal disorders.
